respiratory disease — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
TN1416	Ayanin		IL Receptor , P450 , PARP , PDE
	Ayanin has vasorelaxant activity, it also may have the potential for use in treating allergic asthma.The IC(50) value of Ayanin (quercetin-3,7,4'-O-trimethylether) is 2.2microM for inhibiting interleukin (IL)-4 productio...		IL Receptor , P450 , PARP , PDE
T9911	Tocilizumab		Interleukin
	Tocilizumab (anti-IL-6R) is a humanized monoclonal antibody that binds to the interleukin-6 receptor		Interleukin
T64337	PF-04745637	PF4745637,PF 4745637,PF 04745637,PF-4745637	TRP/TRPV Channel
	PF-04745637 is a potent and selective TRPA1 antagonist with an IC50 of 17 nM[1].		TRP/TRPV Channel
T6850	GSK2292767		PI3K
	GSK2292767 is a potent and selective PI3Kδ inhibitor.		PI3K
T0777	Tilmicosin	LY-177370,EL-870	Antibacterial , Antibiotic
	Tilmicosin (EL-870) is a macrolide antibiotic. It is used in veterinary medicine for the treatment of bovine respiratory disease and ovine respiratory disease associated with Mannheimia haemolytica.		Antibacterial , Antibiotic
T22439	Tilmicosin phosphate		Antibacterial , Antibiotic
	Tilmicosin phosphate, a macrolide antibiotic, is used to treat cattle for pathogens that cause Bovine Respiratory Disease.		Antibacterial , Antibiotic
T15431	Nemiralisib	GSK2269557 (free base),GSK2269557	PI3K
	Nemiralisib（GSK-2269557 free base） is an orally available, potent and specific PI3Kδ inhibitor with a pKi of 9.9.Nemiralisib is used for the treatment of respiratory diseases including chronic obstructive pulmonary disea...		PI3K
T7392	Revefenacin	TD-4208,GSK1160724	AChR
	Revefenacin (TD-4208) is a mAChR antagonist has a high affinity on M3 receptor( Ki : 0.18 nM),and potentially useful for the treatment of respiratory disease.		AChR
TC0039	Vasicinone		Others
	Vasicinone may act as a hepatoprotective agent. (±)-Vasicinone has significant antitussive, expectorant, and bronchodilating activities, which can be used to treat respiratory disease.(S)-Vasicinone exhibits antiprolifer...		Others
T60091	Sodium iodide		Others
	Sodium iodide is an orally available and radioactive compound for the prevention of respiratory disease in pre-weaned dairy cows.		Others
T60522	Letosteine	Viscotiol	Others
	Letosteine (Viscotiol) is an orally active, effective, and safe expectorant that can be used in the study of acute or chronic respiratory diseases, for example, bronchopulmonary disease. Letosteine dissolves bronchial mu...		Others
T2191	Tacrine hydrochloride (hydrate)	Tacrine,Tacrine hydrochloride hydrate,Tetrahydroaminacrine,Tetrahydroaminoacridine	AChR , AChE
	Tacrine hydrochloride hydrate (Tetrahydroaminacrine) is a cholinesterase inhibitor that crosses the blood-brain barrier. Tacrine has been used to counter the effects of muscle relaxants, as a respiratory stimulant, and i...		AChR , AChE
T4960	VASICINE		Anti-infection , AChR
	Vasicine is oxytocic and abortifacient agents.Vasicine, a potential natural cholinesterase inhibitor, has been in development for treatment of Alzheimer's disease. Vasicine can regulate the inflammatory reaction, have gr...		Anti-infection , AChR
T5623	Bisphenol A		Others , Endogenous Metabolite
	Bisphenol A is an endogenous metabolic compound of phenols and is widely used in the production of epoxy resins and polycarbonate plastics. It is reproductive, developmental and systemic toxicant and is often classified ...		Others , Endogenous Metabolite
TN3048	4-Methoxycinnamaldehyde	p-Methoxycinnamaldehyde	RSV
	4-Methoxycinnamaldehyde (p-Methoxycinnamaldehyde) is an active ingredient of Agastache rugosa.4-Methoxycinnamaldehyde has cytoprotective activity against respiratory syncytial virus (RSV) in human laryngeal carcinoma cel...		RSV
T67302	2,3-Pentanedione	Acetylpropionyl	Others
	2,3-Pentanedione is a food additive that also occurs naturally as a fermentation product in beer, wine and yogurt and is released during the roasting of coffee beans. Inhalation of 2,3-Pentanedione is thought to be the c...		Others
T0454	Florfenicol	Nuflor,Aquafen	Others
	Florfenicol (Aquafen) is a fluorinated synthetic analog of thiamphenicol. In the United States, florfenicol is currently used to treat bovine respiratory disease (BRD) associated with Mannheimia (Pasteurella) haemolytica...		Others
T0454L	Florfenicol	SCH-25298,(-)-Florfenicol	Antibacterial , Antibiotic
	Florfenicol (SCH-25298), a fluorinated synthetic analog of thiamphenicol, is currently indicated for the therapy of bovine respiratory disease (BRD) associated with Mannheimia (Pasteurella) haemolytica, Haemophilus somnu...		Antibacterial , Antibiotic
T0056	Oxeladin citrate		Others
	Oxeladin citrate is a highly potent and effective cough suppressant, which can treat all types of cough of various etiologies. It is not related to opium or its derivatives, so treatment with oxeladin is no risk of add...		Others
T79809	ROCK-IN-8		ROCK
	ROCK-IN-8 (Example 4), a ROCK inhibitor, exhibits anti-inflammatory properties and is suitable for respiratory and gastro-intestinal disease research, demonstrating an IC50 value below 100 nM [1].		ROCK